The Twilio Client JavaScript SDK version 1.3 supports WebRTC on the most recent versions of Chrome and Firefox, and provides ORTC support for Microsoft Edge. Desktop browsers which do not support WebRTC/ORTC, including Safari on Mac OS X and Internet Explorer, can use Twilio Client SDK 1.2 which includes a Flash version.

We support the current major revision of the browser and the previous major browser revision. That is to say, if the current release version is N, we test with N and N-1.

Mobile browsers including Safari and Chrome on iOS and Chrome on Android are not supported by Twilio Client; instead we recommend the use of Twilio’s SDKs to develop nativeAndroid and iOS apps.

Other browsers are investigating support for WebRTC and may release WebRTC capable versions in the future. Please refer to this link for the most up-to-date information about browser WebRTC support.